57. B. Hegyi, T. Bányász, T. R. Shannon, Y. Chen-Izu, and L. T. Izu. Electrophysiological Determination of Submembrane Na+ Concentration in Cardiac Myocytes. Biophys. J. 111:1304–1315 (2016). Research Article (pdf)
56. Jian Z, Chen YJ, Shimkunas R, Jian Y, Jaradeh M, Chavez K, Chiamvimonvat N, Tardiff JC, Izu LT, Ross RS, Chen-Izu Y. In Vivo Cannulation Methods for Cardiomyocytes Isolation from Heart Disease Models. PLoS One. 2016 Aug 8;11(8):e0160605. doi:10.1371/journal.pone.0160605. Research Article (pdf)
55. Alexander, A.M., E.K. DeNardo, E. Frazier III, M. McCauley, N. Rojina, Z. Coulibaly, B.E. Peercy, and L.T. Izu. Spontaneous calcium release in cardiac myocytes: Store overload and electrical dynamics. SPORA: A Journal of Biomathematics. 2015 Vol. 1: Iss. 1, Article 6. Research Article (pdf)
54. Awasthi, S., Izu, L., Mao, Z., Jian, Z., Landas, T., Lerner, A., Shimkunas, R., Woldeyesus, R. A., Bossuyt, J., Wood, B. M., Chen, Y. J., Matthews, D. L., Lieu, D. K., Chiamvimonvat, N., Lam, K. S., Chen-Izu, Y., and Chan, J. W. Multimodal SHG-2PF imaging of microdomain Ca2+- contraction coupling in live cardiomyocytes. Circ. Res. 2016 Jan 22;118(2):e19-28. doi: 10.1161/CIRCRESAHA.115.307919. Research Article (pdf)
53. Izu LT, Bányász T, Chen-Izu Y. Optimizing Population Variability to Maximize Benefit. PLoS One. 2015 Dec 9;10(12):e0143475. doi: 10.1371/journal.pone.0143475. eCollection 2015. Research Article (pdf)
52. Uchinoumi H, Yang Y, Oda T, Li N, Alsina KM, Puglisi JL, Chen-Izu Y, Cornea RL, Wehrens XHT, Bers DM. CaMKII-dependent phosphorylation of RyR2 promotes targetable pathological RyR2 conformational shift. J Mol Cell Cardiol. 2016 Sep;98:62-72. doi: 10.1016/j.yjmcc.2016.06.007. Research Article (pdf)
51. Hegyi B, Chen-Izu Y, Jian Z, Shimkunas R, Izu LT, Banyasz T. KN-93 inhibits IKr in mammalian cardiomyocytes. J Mol Cell Cardiol. 2015 Dec;89(Pt B):173-6. Research Article (pdf)
50. Nakajima K, Zhu K, Sun YH, Hegyi B, Zeng Q, Murphy CJ, Small JV, Chen-Izu Y, Izumiya Y, Penninger JM, Zhao M. KCNJ15/Kir4.2 couples with polyamines to sense weak extracellular electric fields in galvanotaxis. Nature Communication 2015 Oct 9; 6:8532. doi: 10.1038/ncomms9532. Research Article (pdf)
49. Chen-Izu, Y, Shaw, RM, Pitt, GS, Yarov-Yarovoy, V, Sack, JT, Abriel, H, Aldrich, RW, Belardinelli, L, Cannell, MB, Catterall, WA, Chazin, WJ, Chiamvimonvat, N, Deschenes, I, Grandi, E, Hund, TJ, Izu, LT, Maier, LS, Maltsev, VA, Marionneau, C, Mohler, PJ, Rajamani, S, Rasmusson, RL, Sobie, EA, Clancy, CE, Bers, DM. Na(+) channel function, regulation, structure, trafficking and sequestration. The Journal of physiology, 593(6): 1347-60 (2015). [Review] Research Article (pdf)
48. Clancy, CE, Chen-Izu, Y, Bers, DM, Belardinelli, L, Boyden, PA, Csernoch, L, Despa, S, Fermini, B, Hool, LC, Izu, L, Kass, RS, Lederer, WJ, Louch, WE, Maack, C, Matiazzi, A, Qu, Z, Rajamani, S, Rippinger, CM, Sejersted, OM, O’Rourke, B, Weiss, JN, Varró, A, Zaza, A. Deranged sodium to sudden death. The Journal of physiology, 593(6): 1331-45 (2015). [Review] Research Article (pdf)
47. Shattock, MJ, Ottolia, M, Bers, DM, Blaustein, MP, Boguslavskyi, A, Bossuyt, J, Bridge, JH, Chen-Izu, Y, Clancy, CE, Edwards, A, Goldhaber, J, Kaplan, J, Lingrel, JB, Pavlovic, D, Philipson, K, Sipido, KR, Xie, ZJ. Na+/Ca2+ exchange and Na+/K+-ATPase in the heart. The Journal of physiology, 593(6): 1361-82 (2015). [Review] Research Article (pdf)
46. Bers, DM, Chen-Izu, Y. Sodium and calcium regulation in cardiac myocytes: from molecules to heart failure and arrhythmia. The Journal of physiology, 593(6): 1327-9 (2015). Editorial (pdf)
45. Banyasz, T, Szentandrássy, N, Magyar, J, Szabo, Z, Nánási, PP, Chen-Izu, Y, Izu, LT. An emerging antiarrhythmic target: late sodium current. Current pharmaceutical design, 21(8): 1073-90 (2015). [Review] Research Article (pdf)
44. Pei-Chi Yang, Yejia Song, Wayne R. Giles, Balazs Horvath, Ye Chen-Izu, Luiz Belardinelli, Sridharan Rajamani, and Colleen Clancy. A Computational modeling approach combined with cellular electrophysiology data predicts therapeutic benefit of targeting late INa. J Physiol, 593(6): 1429-42 (2015). Research Article (pdf.)